US20250025401
2025-01-23
Human necessities
A61K8/65
The patent application discusses systems, compositions, methods, and devices for creating artificial skin substitutes that mimic the morphology and appearance of human skin. These innovations have applications in regenerative medicine and pharmaceuticals, supporting tissue replacement and engineering. The most immediate use is in cosmetics, where pigmented compositions can be incorporated into various skincare and cosmetic foundation products.
This invention relates to tissue engineering and specifically to artificial skin substitutes that replicate the appearance and structure of human skin. It details compositions and constructs that form the basis for various skin substitutes, with methods for making them applicable in both cosmetics and pharmaceuticals. The focus is on creating products that are dependable, reproducible, and commercially viable.
The skin is a complex organ affected by aging, environmental factors, and diseases. Current skin substitutes, including PDMS-based materials, face challenges like cost and non-biodegradability. Alternatives like collagen and keratin offer more biocompatibility but fall short in replicating genuine skin appearance. A significant challenge is color matching to an individual's skin tone, as current technologies rely heavily on melanin combinations.
Color is crucial for both medical and cosmetic applications. Current color cosmetics must balance safety with effectiveness, often using synthetic pigments. However, accurate color matching remains problematic. Some advancements involve imaging technologies for personalized color matching but require a broad color range to be effective.
The disclosed technology offers a comprehensive solution to skin mimicry through customizable products that accurately reflect individual traits and conditions. It emphasizes a digitizable process for producing these products, addressing both structural and color aspects of skin mimicry with advanced polymeric peptide pigments. This approach aims to create a close facsimile of natural skin composition and organization.