METHODS, DEVICES AND SYSTEMS FOR PULMONARY DELIVERY OF ACTIVE AGENTS

Smart overview of the Invention

The invention provides a method for delivering pharmacologically active agents from plant materials via pulmonary routes using a metered dose inhaler. This device is specifically designed to vaporize a precise amount of the agent by controllably heating the plant material. The aim is to achieve specific pharmacokinetic and pharmacodynamic effects in the subject, ensuring consistent and reliable dosing.

Background

Natural substances, such as cannabis, contain numerous active agents with potential therapeutic benefits. Despite their promise, these substances face challenges in medical application due to difficulties in quantifying and controlling dosages. Cannabis, in particular, has shown efficacy in treating conditions like nausea, pain, and neurological disorders but remains controversial due to inconsistent dosing methods and societal perceptions.

Challenges with Current Methods

Traditional methods of cannabis delivery, such as smoking or oral consumption, present several issues. Smoking leads to variable absorption rates and harmful byproducts, while oral methods suffer from slow and unpredictable absorption. Vaporization offers a safer alternative but still lacks precision in dosing, making it difficult to adhere to pharmaceutical standards for treatment regimens.

Innovative Solution

The proposed inhaler device addresses these challenges by providing controlled vaporization of active agents from plant materials. It uses preloaded plant portions with dedicated heating elements to ensure precise and reproducible vaporization. This method allows for accurate dosing based on specific pharmacokinetic and pharmacodynamic effects, which can be adjusted according to individual or population data.

Practical Implications

By enabling precise control over the vaporized amounts of active agents, this invention facilitates the integration of natural substances like cannabis into mainstream pharmaceutical practices. It allows for tailored treatment regimens that can be monitored and adjusted based on real-time data, potentially transforming how these substances are used in medical settings.