US20250264434
2025-08-21
Physics
G01N27/3278
The invention introduces a novel design for fully printable, flexible, and portable biosensors that enable accurate and selective detection of disease biomarkers. These biosensors are designed to operate at the nanoscale, offering rapid response times and the ability to detect ultra-low levels of biomarkers for early diagnosis and intervention. They are applicable in various fields including healthcare, sports, food processing, and telemedicine. Roll-to-Roll Printing Technology is employed to facilitate mass production, ensuring cost-effectiveness and scalability.
Current diagnostic methods such as ELISA are limited by their complexity, cost, and need for skilled personnel. While paper-based biosensors offer a potential alternative, they often deliver only qualitative or semi-quantitative results due to issues like noise interference and signal variability. The invention aims to overcome these limitations by integrating nanotechnology with biosensors to improve sensitivity and selectivity. Additionally, the seamless integration of bio-receptors with transducers addresses signal loss issues seen in conventional devices.
Previous technologies have explored nanostructure biosensors but have not fully addressed the need for flexible, printable biosensors with internet connectivity suitable for mass production. Existing devices often lack the integration needed to minimize signal loss or fail to incorporate advanced data processing capabilities. This invention stands out by providing a comprehensive solution that combines these features, enhancing both the functionality and applicability of biosensors in real-world settings.
The primary goal is to address current technological challenges in designing and manufacturing biosensors that are applicable across diverse domains such as healthcare, sports, and industrial environments. The invention seeks to create biosensors that are not only printable but also capable of detecting biomarkers at concentrations as low as 0.01 ng/ml. These devices are particularly useful for early diagnosis and monitoring of life-threatening conditions like heart attacks.
The proposed solution consists of a biosensing device that is fully printable and flexible, equipped with nanotechnology enhancements for biofunctionalization. This enables precise detection and measurement of specific biomarkers. The device includes a flexible substrate with patterned electrodes and dielectric layers, all integrated into a compact form factor with internet connectivity for data transmission. This configuration ensures reliable performance in detecting and monitoring biomarkers at the nanoscale.