Invention Title:

EGFR INHIBITOR FOR THE TREATMENT OF CANCER

Publication number:

US20250289824

Publication date:
Section:

Chemistry; metallurgy

Class:

C07D487/04

Inventors:

Assignee:

Applicant:

Smart overview of the Invention

The patent application discusses a novel compound designed to inhibit the Epidermal Growth Factor Receptor (EGFR), which plays a crucial role in the development and progression of various cancers. The compound is represented by a general formula (I) and is intended for use in pharmaceutical compositions aimed at cancer treatment.

Compound Details

The compound described in the application is characterized by its unique chemical structure, which is specifically tailored to target and bind to EGFR. This binding inhibits the receptor's activity, potentially slowing down or stopping cancer cell proliferation. The detailed chemical structure of the compound is essential for its specificity and effectiveness in targeting cancer cells.

Compositions

The application outlines various compositions that include the novel compound. These compositions are formulated to maximize the compound's therapeutic potential. They may include additional agents that enhance stability, absorption, or delivery of the active ingredient to the targeted cancer cells, ensuring optimal efficacy.

Methods of Use

The methods proposed involve administering the compound to patients diagnosed with cancers characterized by overexpression or mutation of EGFR. The administration can be tailored based on the type and stage of cancer, as well as patient-specific factors, potentially offering a personalized treatment approach.

Potential Benefits

Key benefits of this invention include:

  • Targeted inhibition of EGFR, potentially leading to fewer side effects compared to non-specific treatments.
  • Possibility of use in combination therapies, enhancing overall treatment outcomes.
  • Personalized treatment options based on individual patient profiles and specific cancer types.